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Viral DNA incorporated into host cell DNA is known as a(n)


A) capsid.
B) prophage.
C) envelope.
D) phage.

E) B) and C)
F) A) and C)

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A eukaryotic cell has a nuclear envelope that allows tRNA molecules, but not mRNA molecules, to leave the nucleus. Which of the following processes will not be able to take place in this cell?


A) DNA replication
B) tRNAs binding to codons
C) RNA being made from DNA
D) tRNAs binding to amino acids

E) A) and B)
F) None of the above

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Considering only the steps that take place during translation, which of the following is not needed in order for translation to occur?


A) DNA template
B) ribosomes
C) tRNA
D) sources of energy, including ATP

E) A) and C)
F) A) and D)

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Which of the following statements about eukaryotic RNA is true?


A) Introns are added to the RNA.
B) Exons are spliced together.
C) A small cap of extra nucleotides is added to both ends of the RNA.
D) The modified RNA molecule is transported into the nucleus.

E) A) and C)
F) A) and D)

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Which of the following takes place during translation?


A) the conversion of genetic information from the language of nucleic acids to the language of proteins
B) the conversion of genetic information from DNA nucleotides into RNA nucleotides
C) the conversion of genetic information from the language of proteins to the language of enzymes
D) DNA replication

E) B) and D)
F) C) and D)

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The shape of a DNA molecule is most like


A) a set of railroad tracks.
B) a wooden ladder.
C) a twisted rope ladder.
D) beads on a string.

E) C) and D)
F) None of the above

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A physical or chemical agent that changes the nucleotide sequence of DNA is called a(n)


A) terminator.
B) transposon.
C) mutagen.
D) anticodon.

E) A) and D)
F) A) and C)

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Where do transcription and translation occur in prokaryotic cells?


A) on the plasma membrane
B) in the nucleus
C) in the cytoplasm
D) in chromatophores

E) B) and C)
F) A) and D)

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Which of the following occurs when RNA polymerase attaches to the promoter DNA?


A) elongation of the growing RNA molecule
B) termination of the RNA molecule
C) initiation of a new RNA molecule
D) initiation of a new polypeptide chain

E) B) and C)
F) A) and D)

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Why does a DNA strand grow only in the 5' to 3' direction?


A) because DNA polymerases can only add nucleotides to the 3' end of the growing molecule
B) because DNA polymerases can only add nucleotides to the 5' end of the growing molecule
C) because the DNA molecule only unwinds in the 5' to 3' direction
D) because DNA polymerase requires the addition of a starter nucleotide at the 5' end

E) A) and D)
F) B) and C)

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We would expect that a 15-nucleotide sequence that includes a stop codon at the end (as part of the 15-nucleotide sequence) will direct the production of a polypeptide that consists of


A) two amino acids.
B) three amino acids.
C) four amino acids.
D) five amino acids.

E) A) and B)
F) B) and D)

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What nucleotide sequence would be found on the partner DNA strand of the strand shown? What nucleotide sequence would be found on the partner DNA strand of the strand shown?   A) ACTGT B) UGAGA C) TGACA D) TGUGU


A) ACTGT
B) UGAGA
C) TGACA
D) TGUGU

E) A) and B)
F) All of the above

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One type of virus that infects bacteria is called a


A) phage.
B) retrovirus.
C) rhinovirus.
D) coronavirus.

E) None of the above
F) All of the above

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The way that genetic material of a bacteriophage enters a bacterium is most like the way that


A) a drug is injected with a hypodermic needle.
B) a person swallows a pill.
C) skin lotion is rubbed onto the hands.
D) water soaks into a sponge.

E) A) and D)
F) B) and D)

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Conjugation between a bacterium that lacks an F factor (F⁻) and a bacterium that has an F factor on its chromosome (F⁺) could produce which of the following results?


A) The F⁻ bacterium ends up carrying one or more plasmids from the F⁺ bacterium; the F⁺ bacterium is unchanged.
B) The F⁺ bacterium ends up with a recombinant chromosome that carries some genes from the F⁻ bacterium, and the F⁻ bacterium ends up with an unaltered chromosome.
C) The F⁺ bacterium ends up with a recombinant chromosome that carries some genes from the F⁻ bacterium, and the F⁻ bacterium ends up with a chromosome that lacks those genes.
D) The F⁻ bacterium ends up with a recombinant chromosome that carries some genes from the F⁺ bacterium, and the F⁺ bacterium ends up with an unaltered chromosome.

E) None of the above
F) All of the above

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Which of the following enzymes does HIV use to synthesize DNA on an RNA template?


A) ligase
B) RNA polymerase
C) reverse transcriptase
D) DNA convertase

E) C) and D)
F) A) and B)

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Which of the following statements regarding RNA is false?


A) RNA uses the sugar dextrose.
B) RNA uses the nitrogenous base uracil.
C) One RNA molecule can include four different nucleotides in its structure.
D) RNA molecules have a sugar-phosphate backbone.

E) A) and B)
F) All of the above

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Below are three statements. Which of the following choices properly matches the statements with the correct biological processes? I. This occurs in the nucleus of eukaryotic cells. II) Transfer RNAs bind amino acids in the cytoplasm. III) A polymerase enzyme is required.


A) I: replication; II: translation; III: transcription
B) I: translation; II: translation; III: replication
C) I: transcription; II: translation; III: translation
D) I: replication; II: transcription; III: replication

E) None of the above
F) C) and D)

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Which of the following statements about treatment or prevention of a prion infection is true?


A) Antibiotic therapies such as penicillin are very effective cures.
B) High doses of anti-inflammatory drugs such as ibuprofen reduce the symptoms of prion infections.
C) Preventative vaccines have recently been shown to be effective in preventing prion infections.
D) There is no known treatment or cure for prion infections.

E) B) and C)
F) None of the above

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After reading the paragraphs below, answer the questions that follow. Diabetes mellitus is a metabolic disease that is characterized by the buildup of glucose in the blood, or hyperglycemia. Diabetes results either from the pancreas not being able to produce the hormone insulin (type 1 diabetes) or if the body's cells become resistant to insulin (type 2 diabetes) . Insulin is a protein that binds to receptors on cell surfaces to allow glucose to enter the cell. In order to manage the disease, type 1 diabetics require frequent insulin injections. Until the 1970s, insulin was obtained from processing the pancreases of large mammals such as cows and pigs; it was then purified for medicinal use. This all changed in the 1970s with the advent of recombinant DNA technology, which allows scientists to insert genes from other species into bacterial plasmids and have bacteria produce proteins from these other species' genes. In 1978, the gene that codes for human insulin was added to a bacterial plasmid and bacteria were used to produce human insulin. These bacteria acted as mini-factories that produced human insulin for type 1 diabetes patients. Today, the production of human insulin from bacteria is commonplace and is a multibillion dollar market for pharmaceutical companies. -Suppose that the human insulin protein that was produced by the bacteria was much shorter than it should be. Upon further investigation, it was found that the DNA of the human insulin gene had a mutation while in the bacterial cells. What type of mutation could not result in these observations?


A) nucleotide insertion
B) silent mutation
C) nucleotide deletion
D) nonsense mutation

E) All of the above
F) A) and D)

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