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The M protein enhances the virulence of Streptococcus by preventing phagocytosis.

A) True
B) False

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Symptoms of intense inflammation and shock occur in some gram-positive bacterial infections due to


A) A-B toxins.
B) lipid A.
C) membrane-disrupting toxins.
D) superantigens.
E) erythrogenic toxin.

F) A) and E)
G) C) and D)

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For what reason might the ID50 for Salmonella Typhi decrease when a rat simultaneously ingests sulfa drugs with the pathogen?


A) It would not;the ID50 goes up.
B) The antimicrobial interferes with the microbiome enabling the pathogen to more easily establish infection.
C) There would not be an effect on the ID50.
D) The antimicrobial inactivates stomach acid and allows the pathogen to more readily pass to the intestine.
E) Salmonella Typhi becomes stronger in the presence of sulfa drugs.

F) B) and E)
G) B) and D)

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All of the following organisms produce exotoxins EXCEPT


A) Salmonella typhi.
B) Clostridium botulinum.
C) Corynebacterium diphtheriae.
D) Clostridium tetani.
E) Staphylococcus aureus.

F) None of the above
G) A) and C)

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Which of the following cytopathic effects is cytocidal?


A) inclusion bodies
B) giant cells
C) antigenic changes
D) transformation
E) release of enzymes from lysosomes

F) D) and E)
G) All of the above

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Which of the following is an example of direct damage due to bacterial infection?


A) the uncontrolled muscle contractions in Clostridium tetani infection
B) the invasion and lysis of intestinal cells by E.coli
C) the hemolysis of red blood cells in a staphylococcal infection
D) the fever,nausea,and low blood pressure in a Salmonella infection
E) the excessive secretion of fluids in a Vibrio cholera infection

F) D) and E)
G) All of the above

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Endotoxins in sterile injectable drugs could cause


A) infection.
B) septic shock symptoms.
C) giant cell formation.
D) nerve damage.
E) no damage,because they are sterile.

F) B) and E)
G) B) and D)

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Injectable drugs are tested for endotoxins by


A) the Limulus amoebocyte lysate test.
B) counting the viable bacteria.
C) filtering out the cells.
D) looking for turbidity.
E) culturing bacteria.

F) D) and E)
G) A) and B)

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Infections with some viruses may induce chromosomal changes that alter the growth properties of host cells.

A) True
B) False

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The ID₅₀ is


A) a measure of pathogenicity.
B) the dose that will cause an infection in 50 percent of the test population.
C) the dose that will kill some of the test population.
D) the dose that will cause an infection in some of the test population.
E) the dose that will kill 50 percent of the test population.

F) D) and E)
G) All of the above

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Table 15.1  Bacterium  Portal of Entry  D50  Staphylococcus aureus  Wound <10 Staphylococcus aureus  Wound + Ampicillin 300\begin{array} { | l | l | l | } \hline \text { Bacterium } & \text { Portal of Entry } & \text { D50 } \\\hline \text { Staphylococcus aureus } & \text { Wound } & < 10 \\\hline \text { Staphylococcus aureus } & \text { Wound + Ampicillin } & 300 \\\hline\end{array} Table 15.1 shows the ID₅₀ for Staphylococcus aureus in wounds with and without the administration of ampicillin before surgery.Based on the data,the administration of ampicillin before surgery


A) decreases the risk of staphylococcal infection.
B) increases the risk of staphylococcal infection.
C) has no effect on risk of infection.
D) replaces tetracycline.
E) The answer cannot be determined based on the information provided.

F) A) and B)
G) A) and C)

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Antibiotics can lead to septic shock if used to treat


A) viral infections.
B) gram-negative bacterial infections.
C) gram-positive bacterial infections.
D) protozoan infections.
E) helminth infestations.

F) B) and E)
G) D) and E)

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Nonpathogenic Vibrio cholerae can acquire the cholera toxin gene by


A) phagocytosis.
B) lysogenic conversion.
C) conjugation.
D) transformation.
E) infecting a pathogenic Vibrio cholerae.

F) None of the above
G) B) and D)

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Which pathogen and virulence factor are mismatched?


A) Streptococcus pneumoniae - capsule
B) Streptococcus pyogenes - M protein
C) Clostridium - hyaluronidase
D) Shigella sonnei - coagulase
E) Neisseria gonorrhoeae - IgA protease

F) A) and B)
G) None of the above

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Compare and contrast endotoxins and exotoxins.Why are exotoxins more potent than endotoxins?

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Answered by ExamLex AI

Answered by ExamLex AI

Endotoxins and exotoxins are both types ...

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All of the following are used by bacteria to attach to host cells EXCEPT


A) M protein.
B) ligands.
C) fimbriae.
D) capsules.
E) A-B toxins.

F) C) and D)
G) B) and C)

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Superantigens produce intense immune responses by stimulating lymphocytes to produce


A) endotoxins.
B) exotoxins.
C) cytokines.
D) leukocidins.
E) interferons.

F) A) and D)
G) A) and B)

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Lysogenic bacteriophages contribute to bacterial virulence because bacteriophages


A) give new gene sequences to the host bacteria.
B) produce toxins.
C) carry plasmids.
D) kill the bacteria,causing release of endotoxins.
E) kill human cells.

F) A) and D)
G) A) and C)

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All of the following contribute to a pathogen's invasiveness EXCEPT


A) toxins.
B) capsules.
C) cell wall components.
D) hyaluronidase.
E) coagulases.

F) C) and E)
G) All of the above

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Cholera toxin polypeptide A binds to surface gangliosides on target cells.If the gangliosides were removed,


A) polypeptide A would bind to target cells.
B) polypeptide A would enter the cells.
C) polypeptide B would not be able to enter the cells.
D) Vibrio would not produce cholera toxin.
E) Vibrio would bind to target cells.

F) None of the above
G) A) and D)

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