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The kidneys are the organs that are primarily responsible for maintaining constancy of the volume and electrolyte composition of the internal fluid environment.

A) True
B) False

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____________________ is the inability to prevent the discharge of urine.

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urinary in...

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The ____ establish the medullary vertical osmotic gradient by means of countercurrent multiplication.


A) loops of Henle of juxtamedullary nephrons
B) loops of Henle of cortical nephrons
C) vasa recta of juxtamedullary nephrons
D) vasa recta of cortical nephrons
E) vasopressin-secreting cells

F) None of the above
G) B) and C)

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During reabsorption, for the most part chloride ions:


A) pass between cells
B) move down their electrical gradient
C) move against their concentration gradient
D) both (a) and (b)
E) all of the above

F) B) and D)
G) B) and C)

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Describe how the vertical osmotic gradient is used to create urine of various dilutions.

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The counter current system of the loop o...

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Secretion of organic ions takes place in the:


A) Bowman's capsule.
B) loop of Henle.
C) proximal tubule.
D) collecting duct.
E) glomerulus.

F) D) and E)
G) A) and B)

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Afferent arteriolar vasoconstriction ____ blood flow into the glomerulus, which causes the glomerular-capillary blood pressure to ____, leading to a(n) ____ in the net filtration pressure and a resultant ____ in the GFR.


A) increases, increase, increase, increase
B) decreases, decrease, decrease, decrease
C) increases, increase, decrease, decrease
D) decreases, decrease, increase, increase
E) none of these answers.

F) A) and C)
G) C) and E)

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The glomerular filtrate


A) is a protein-free plasma.
B) is formed as a result of passive forces acting across the glomerular membrane.
C) does not contain foreign compounds because these substances are secreted by special transport mechanisms in the proximal tubule instead.
D) both (a) and (b) above.
E) all of these answers.

F) All of the above
G) B) and C)

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Explain how both voluntary and involuntary responses are associated with micturition.

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The emptying of the bladder is a combina...

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Match chemicals below with the correct characteristic. -It inhibits Na+ reabsorption by the renal tubules.


A) renin
B) angiotensinogen
C) angiotensin I
D) angiotensin II
E) aldosterone
F) atrial natriuretic peptide

G) All of the above
H) E) and F)

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Which of the following statements regarding tubular reabsorption is incorrect? Tubular reabsorption


A) refers to the movement of a substance from the tubular fluid to the peritubular capillary blood.
B) is important for the conservation of substances important to the body, such as Na+, Cl-, glucose, and amino acids.
C) can occur by active or passive transport mechanisms.
D) involves the process of transepithelial transport.
E) takes place only in the proximal tubule.

F) A) and B)
G) B) and C)

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The glomerular capillary blood pressure is higher than capillary pressure elsewhere in the body primarily because the afferent arteriole has a larger diameter than the efferent arteriole.

A) True
B) False

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Indicate whether the first item in the statement increases, decreases, or has no effect on the second item by filling in the appropriate letter using the following answer code. -Increased K+ in body fluids______ renin secretion.


A) increases
B) decreases
C) has no effect on

D) All of the above
E) A) and B)

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Match the nephron structure to the characteristics -fluid entering is this structure is hypertonic, but when it leaves is hypotonic


A) afferent arteriole
B) glomerulus
C) efferent arteriole
D) Bowman's capsule
E) proximal tubule
F) descending limb of loop of Henle
G) ascending limb of loop of Henle
H) distal tubule
I) collecting duct

J) B) and I)
K) A) and I)

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Indicate whether the first item in the statement increases, decreases, or has no effect on the second item by filling in the appropriate letter using the following answer code. -Increased angiotensin II activation _____ aldosterone secretion.


A) increases
B) decreases
C) has no effect on

D) All of the above
E) A) and C)

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Filtration slits:


A) provide a pathway through which fluid from the glomerulus can enter the Bowman's capsule..
B) allow proteins to pass into the filtrate
C) are not found in all nephrons
D) do not allow nutrients to pass into the filtrate
E) are important in the ability of the kidneys to produce urine of varying concentration.

F) None of the above
G) B) and E)

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The three major processes involved in urine formation are filtration, reabsorption, and excretion.

A) True
B) False

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Indicate whether the first item in the statement increases, decreases, or has no effect on the second item by filling in the appropriate letter using the following answer code. -Increased aldosterone secretion _____ Na+ reabsorption.


A) increases
B) decreases
C) has no effect on

D) All of the above
E) B) and C)

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